Creams and ointments, whats the difference, which is best. This table refers more generally to the release of a typical nonelectrolyte primarily lipophilic drug. Generic development of topical dermatologic products. Qc tests for ointments and creams authorstream presentation. Creams, lotions, gels, ointments, and pastes are examples of different types of formulations that are used as semisolid dosages. Ointments, creams, and gels dds ppt pjt slideshare. Pharmaceutical ointments and pastes general description pharmaceutical ointments are semisolid systems that are applied externally, primarily to the skin and also to mucous membranes, e. However, nonmedicated ointments are commonly used due to their emollient lubricating properties. Process validation of ointment creams verification and. Ointments are semisolid preparations that are thicker than creams but thinner than pastes. Difference between ointment and cream ointment vs cream. The aim of present work was to develop a semisolid preparation ointment, gel, cream of thiocolchicoside which is a centrally acting skeletal muscle relaxant for the effective treatment of.
There are three primary types of topical herbal treatments. Semisolid dosage forms intended for topical application unmedicated ones protectants or lubricants. Infused oils are made by steeping herbs in a carrier oil like olive or almond to extract. Formulation and evaluation of antiseptic polyherbal ointment p. Ointments, creams, and gels 4 legit free download as powerpoint presentation. Oil any good quality vegetable oil can be used to make your ointments. See creams, topical solutions, and topical suspensions, herein. In general, people prefer using creams to ointments since they are less sticky and heavy on the skin. You can edit text and objects, add notes, manage pages, merge pdfs, protect files, and much more with the pdf. Even though we think of creams as being moisturizing, given their higher water content and the evaporation that occurs following application, creams are better than ointments. Creams are semisolid preparations containing one or more medical agents dissolved or dispersed in either an oilinwater emulsion or in another type of waterwashable base. After you complete your checkout, you will receive an email with a download link for a png file you can save to your computer and read with any pdf reader such as the adobe acrobat reader. After you complete your checkout, you will receive an email with a download link for a png file you can save to your computer and read with any pdf.
The main difference is that cream and gel are generally waterbased, while ointment is oilbased. Difference between ointment and cream difference between. Can creams and ointment be kept in a residents room. Fight infections and relieve pain with our topical formulations. Expiration dates are checked on each item prior to use. Make sure that you follow closely the procedures for preparation. For herbal formulations, an ointment is made by emulsifying oil phase in water while the mixture is warm, then letting the formulation congeal at room temperature. Ointments are better for concentrated areas, also because they tend to be stronger than creams and tend to heal the area faster. Portions of the pdf ecapproved taxonomy charts and glossary.
Ointments may be better to use on sensitive skin since many creams are manufactured with sensitizing preservatives. Cream emulsion of water and oil classified as oil in water ow or water in oil wo emulsions ow creams e. Topical dermatologic products, which can be administered easily and are convenient in terms of portability, are used in treating a variety of disorders. Principle premises and equipment european commission. Creams, gels, and ointments topical medication solution scribd. Oct 09, 2012 as such, the skin is susceptible to various disorders and diseases. Creams may be considered pharmaceutical products as even cosmetic creams are based on techniques developed by pharmacy and unmedicated creams are highly used in a variety of skin conditions dermatoses. Other ointment bases are composed largely of lipid. Ointments and creams introduction ointments are used topically as protectants, antiseptics, emollients, antipruritics, kerotolytics and astringents. Manufacture of liquids, creams and ointments principle liquids, creams and ointments may be particularly susceptible to microbial and other contamination during manufacture. The difference between gel, cream and ointment leaftv. Start with overthecounter products and lifestyle changes. Current definitions of lotions, gels, creams and ointments vary depending on literature source, market. Furthermore, dermatologists often prefer creams to ointments as creams have few ingredients beyond the base oil or fat.
A topical medication is a medication that is applied to body surfaces such as the skin. Experimental studies on the penetration of the following substances. Creams may represent the most popular and traditional use of emulsions. There are a lot of ingredients for the preparation of creams and ointments. Therefore special measures must be taken to prevent any contamination. Creams are generally less potent than ointments of the same medication, and they often contain preservatives, which can cause irritation, stinging, and allergic reac.
Many patients and physicians prefer creams to ointments because they are easier to spread and remove than many ointments. Epub ahead of print antimicrobial ointments and methicillinresistant. Production of pharmaceutical creams and ointments view pdf pharmaceutical preparations for treatment of conditions such as rashes, skin irritation, stings, fungal infections, etc. Sample preparation was fairly easy and measurement times were under 5 minutes per sample. Topicals preparations applied to the skin either for their physical effects or for the specific effect of a. Recommendations for providing basic compounded creams and ointments for healthcare providers working in nonpharmacy settings. Typically, they have an oily or greasy consistency and can appear stiff as they are applied to the skin. It is thicker than lotion, but thinner than ointment. Ointment introduction ointments and creams are used topically for several purposes, e.
Hemorrhoids often get better without surgery or even procedures your doctor can do in the office. Semisolid dosage forms include ointments and creams. Some creams contain oil, but at a lower concentration than in ointment. Creams and ointments pharmaceutical emulsions wiley. Pdf formulation and evaluation of semisolid preparation. A cream is a preparation usually for application to the skin. Lets start with the basic stuff that is needed for simple ointments. Cold cream type, hydrous lanolin, rose water ointment, hydrocream, eucerin, nivea. Oct 23, 2016 vaginal ointments these ointments are applied to the vulvovaginal area or inside the vagina. Nov 28, 2012 ointments allow greater penetration of the active ingredient in the topical medication, whether it is an antibiotic, steroid, or antifungal medication. Meet icecream pdf editor intuitive free pdf editor for windows that enables you to create and edit pdf files. There are some basic substances and lots and lots of special stuff. Particle size and shape characterization by automatic image analysis can be a valuable tool for the pharmaceutical and cosmetics industry making ointments and creams.
Production of pharmaceutical creams and ointments us. How to use eye ointments and gels properly using a mirror or having someone else give you the eyedrops may make this procedure easier. Download free and accurate pdf guitar tabs for cream songs made from power tab files. This rule applies to treatment of minor injuries that occur in the workplace. Rheology of creams, ointments and lotions a simple oscillation stress sweep test reveals the significant differences in the behaviour of a lotion, a cream and an ointment. Ointments are generally used as emollients or for the application of actives to the skin, as well as for protective purposes where occlusion is required and miscibility with skin secretions is anticipated. Mar 15, 2010 various categories of drugs such as antibacterials, antifungals, and antivirals are incorporated into these products, which show their activity on the surface layers of tissues or penetrate into internal layers to reach the site of action. What records should be made of the administration of creams and ointments. Ointments contain drug that may act on the skin or be. Ointments ointments are semisolids intended for external application to the skin or mucous membranes. The ointment formulation consists of active and inactive ingredients added to a base. Ointments and creams by sajjad lcps 03006389123 authorstream presentation. Definition topical semisolid dosage forms are normally presented in the form of creams, gels, ointments, or pastes.
Ointments and creams are the semisolid dosage forms and intended for topical application to the skin, placed on the surface of eye, or used nasally, vaginally or rectally for therapeutic or protective action or cosmetic function. Process validation of ointment creams free download as powerpoint presentation. Adequate first aid supplies shall be readily available. Some are easily over the counter while are some are prescribed by the doctor. Ointments and creams are the semisolid dosage forms and intended for topical application to the skin, placed on the surface of eye, or used nasally, vaginally or. They contain one or more active ingredients dissolved or uniformly dispersed in a suitable base and any suitable excipients such as emulsifiers. Semisolid dosages are mostly administered topically, transdermal, or in the case of some gels via subcutaneous injection and can contain many ingredients 510 or more. Preparation of ointment bases the pharmaceutics and.
S pharmacopeia usp classifies ointment bases as hydrocarbon bases oleaginous. List of medications that may stain or damage clothing revised 11172016 please note this list is to be used as a guide as there are multiple manufacturers, dosage forms, and excipients. Creams, gels, and ointments free download as powerpoint presentation. Creams, ointments, and gels generally are referred to as semisolid dosage forms. A beginners guide to making herbal salves and lotions. Ointments, creams, and gels 4 legit topical medication. Ointments and pastes are among the dosage forms used primarily to deliver a drug topically to the skin for various disorders. Cream is a comparatively rich emulsion of milk fat. Ointments and creams by sajjad lcps 03006389123 authorstream. Typically, medicated ointments are used for the treatment of infection, inflammation and pruritus.
Since they are very moisturizing, they are good for dry skin. Goyal department of pharmaceutics, isf college of pharmacy, moga, punjab abstract skin is the largest organ of the human body and plays the most important role in protecting against pathogen and foreign matter. Cream and cream products have a variety of compositions and are mostly defined according to fat content, which ranges from 10 to more than 50%. The ointment base is very important, as it determines the use of the ointment. Medicated ones local and systemic effect topical dermatological product designed to deliver drug into the skin.
What is the difference between gel, ointment, cream. Pharmaceutical pastes are generally composed of ointment. Drug product preparation liquid, lotions, ointments and. Moisturizing ointments are used as moisturizersnormally a combination of 80 percent oil and 20 percent water. They are favoured because of their inherent spreadability. The purpose of this chapter is to give you basic knowledge about ointment bases and their ingredi. Hence, it is easier to spread creams over large areas.
Liquids, creams and ointments may be particularly susceptible to microbial and other contamination during manufacture. Ointments are greasier and they have thicker consistencies. So you may not be able to spread ointments over large areas of the skin. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Janfeb 1999 dental compounding view all articles in issue. Basf offers a broad selection of oils, emulsifiers, viscosity enhancers and solvents to equip the formulator to be able to produce a wide range of lotions, creams and gel emulsions. Ointments have shown to relieve infective eye diseases too. Things to consider is the administration of creams, ointments.
Nasal ointments these are used in the topical treatment of nasal mucosa. They usually contain less than 20% water and volatiles and more than 50% hydrocarbons, waxes, or polyols as the vehicle. Ointments are preparations for external use, intended for application to the skin. Creams on the other hand have lighter consistencies so these work better if you want to cover large areas. Unlike homemade ointments, homemade creams are designed to soften and blend into the skin, and are made with a mixture of water fats and oils. Antimicrobial ointments and methicillinresistant staphylococcus aureus usa300. Formulation and evaluation of ointment and cream with. Varies depending upon specific content of the ointment base and the relative polarity of the drugs incorporated. The most common drug products applied to the skin for systemic effects are referred to as selfadhering transdermal drug delivery systems tds or transdermal patches.
Ointment and creams are both types of topical medication. The spreadability factor is also a major difference between ointment and cream. As vagina is more susceptible to infections, the ointment should be free from microorganisms, moulds and yeasts. Topical preparations exist in many forms, such as ointments, gels, creams, lotions, solutions, suspensions, foams, and shampoos. The use of closed systems for processing and transfer is recommended in order to protect. Creams for application to mucous membranes such as those of the rectum or vagina are also used. Semisolid dosage form ointments, creams, paste and gels are. Ointments also have a low risk of sensitization and low irritation risk.
Each ointment base type has different physical characteristics and therapeutic uses based upon the nature of its components. Formulation and evaluation of antiseptic polyherbal ointment. You can split pdf into singlepage files, split by groups of pages and even get rid of certain pages using one of the splitting modes of the software. However, nonmedicated ointments are commonly used due to their emollientlubricating properties. Influence of manufacturing process variables on the. Ointment bases recognized for use as vehicles fall into. Prepare 120 g of each of the following five ointments on a ww basis. Ointment bases the pharmaceutics and compounding laboratory. This article focuses on the formulation, evaluation, and regulatory features of ointments, creams, and gels.
494 564 71 1364 349 749 1144 800 730 561 308 1469 15 27 1260 1340 689 1266 455 876 1427 201 977 576 506 541 404 1116